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2017

A cytosolic Ezh1 isoform modulates a PRC2–Ezh1 epigenetic adaptive response in postmitotic cells. Nature Structural & Molecular Biology. 2017

H2A monoubiquitination in Arabidopsis thaliana is generally independent of LHP1 and PRC2 activity. Genome Biology. 2017, 18:69

Human Nup98 regulates the localization and activity of DExH/D-box helicase DHX9. eLife. 2017, 6:e18825

Maintenance of macrophage transcriptional programs and intestinal homeostasis by epigenetic reader SP140. Science Immunology. 2017, 2(9):eaag3160

Identification of quiescent and spatially restricted mammary stem cells that are hormone responsive. Nature Cell Biology. 2017, 19:164–176

Combining ATAC-seq with nuclei sorting for discovery of cis-regulatory regions in plant genomes. Necleic Acids Research. 2017, 45(6):e41

2016

Dpy30 is critical for maintaining the identity and function of adult hematopoietic stem cells. The Journal of Experimental Medicine. 2016, 213(11):2349-2364

Satb2 determines miRNA expression and long-term memory in the adult central nervous system. eLife. 2016, 5:e17361

m6A modulates neuronal functions and sex determination in Drosophila. Nature. 2016, 540:242–247.

Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a. Nature Cell Biology. 2016, 18(11):1127–1138

Comprehensive genome and epigenome characterization of CHO cells in response to evolutionary pressures and over time. Biotechnology and Bioengineering. 2016, 113(10):2241-2253.

A comprehensive comparison of tools for differential ChIP-seq analysis. Briefings in Bioinformatics. 2016, 17(6): 953-966.

metagene Profiles Analyses Reveal Regulatory Element’s Factor-Specific Recruitment Patterns. PLoS Comput Biol. 2016, 12(8): e1004751.

Mouse MORC3 is a GHKL ATPase that localizes to H3K4me3 marked chromatin. PNAS Aug, 2016

TCGA Workflow: Analyze cancer genomics and epigenomics data using Bioconductor packages. F1000Research. 2016, 5:1542.

Cistrome-based Cooperation between Airway Epithelial Glucocorticoid Receptor and NF-κB Orchestrates Anti-inflammatory Effects. The Journal of Biological Chemistry 2016, 291:12673-12687.

Obesity and Bariatric Surgery Drive Epigenetic Variation of Spermatozoa in Humans. Cell Metabolism 2016, 23(2):369-378.

ReactomePA: an R/Bioconductor package for reactome pathway analysis and visualization. Molecular BioSystems. 2016, 12(2):477-479.

2015

Elf5-centered transcription factor hub controls trophoblast stem cell self-renewal and differentiation through stoichiometry-sensitive shifts in target gene networks. Genes & Development 2015, 29:2435-2448.

Response Element Composition Governs Correlations between Binding Site Affinity and Transcription in Glucocorticoid Receptor Feed-forward Loops. The Journal of Biological Chemistry 2015, 290:19756-19769.

Common binding by redundant group B Sox proteins is evolutionarily conserved in Drosophila. BMC Genomics 2015, 16:292.