meshes: MeSH Enrichment and Semantic analyses
MeSH (Medical Subject Headings) is the NLM controlled vocabulary used to manually index articles for MEDLINE/PubMed.
MeSH terms were associated by Entrez Gene ID by three methods,
This association is fundamental for enrichment and semantic analyses.
meshes supports enrichment analysis (over-representation and gene set enrichment analysis) of gene list or whole expression profile.
The semantic comparisons of MeSH terms provide quantitative ways to
compute similarities between genes and gene groups. meshes implemented five
methods proposed by
Wang respectively and
supports more than 70 species.
meshes is easy, follow the guide on the Bioconductor page:
## try http:// if https:// URLs are not supported source("https://bioconductor.org/biocLite.R") ## biocLite("BiocUpgrade") ## you may need this biocLite("meshes")
- Over-representation analysis
- Gene set enrichment analysis
- MeSH term semantic similarity
- Gene semantic similarity
Find out details and examples on Documentation.