# screen shot

mac上有fink支持debian一样的apt-get，还有原生的macport，gentoo的portage也支持，我选择使用netbsd的pkgsrc来安装各种开源软件。

# Five things biologists should know about statistics

Ewan Birney最近的一篇博文（Five statistical things I wished I had been taught 20 years ago ）讲述了统计对于生物学的重要性。

Ewan所谈及的五个方面分别是：

1. Non parametric statistics. These are statistical tests which make a bare minimum of assumptions of underlying distributions; in biology we are rarely confident that we know the underlying distribution, and hand waving about central limit theorem can only get you so far. Wherever possible you should use a non parameteric test. This is Mann-Whitney (or Wilcoxon if you prefer) for testing “medians” (Medians is in quotes because this is not quite true. They test something which is closely related to the median) of two distributions, Spearman’s Rho (rather pearson’s r2) for correlation, and the Kruskal test rather than ANOVAs (though if I get this right, you can’t in Kruskal do the more sophisticated nested models you can do with ANOVA). Finally, don’t forget the rather wonderful Kolmogorov-Smirnov (I always think it sounds like really good vodka) test of whether two sets of observations come from the same distribution. All of these methods have a basic theme of doing things on the rank of items in a distribution, not the actual level. So - if in doubt, do things on the rank of metric, rather than the metric itself.

# Xming-windows下远程linux桌面

X11Forwrding yes


# Bootstrap Method

a <- c(seq(1:10), rnorm(50))